血液腫瘍疾患

Hamada S, Miyamoto J, Oshiro T, Yagi T, Kiyuna S, Uehara T, Matsuda T, Higa T, Hyakuna N, Nakanishi K. Possible involvement of IL-6-producing tissue-resident macrophages in early-onset pericardial effusion pathogenesis after hematopoietic  stem cell transplantation. Pediatr Blood Cancer. doi: 10.1002/pbc.26982, 2017
 
Hirabayashi S, Seki M, Hasegawa D, Kato M, Hyakuna N, Shuo T, Kimura S, Yoshida K, Kataoka K, Fujii Y, Shiraishi Y, Chiba K, Tanaka H, Kiyokawa N, Miyano S, Ogawa S, Takita J, Manabe A.  Constitutional abnormalities of IDH1 combined with secondary mutations predispose a patient with Maffucci syndrome to acute lymphoblastic leukemia. Pediatr Blood Cancer. 64. doi: 10.1002/pbc.26647, 2017
 
Lévy R, Okada S, Béziat V, Moriya K, Liu C, Chai LY, Migaud M, Hauck F, Al Ali A, Cyrus C, Vatte C, Patiroglu T, Unal E, Ferneiny M, Hyakuna N, Nepesov S, Oleastro M, Ikinciogullari A, Dogu F, Asano T, Ohara O, Yun L, Della Mina E, Bronnimann D, Itan Y, Gothe F, Bustamante J, Boisson-Dupuis S, Tahuil N, Aytekin  C, Salhi A, Al Muhsen S, Kobayashi M, Toubiana J, Abel L, Li X, Camcioglu Y, Celmeli F, Klein C, AlKhater SA, Casanova JL, Puel A. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency. Proc Natl Acad Sci U S A. 113:E8277-E8285, 2016
 
Umeda K, Adachi S, Tanaka S, Miki M, Okada K, Hashii Y, Inoue M, Cho Y, Koh K, Goto H, Kajiwara R, Hyakuna N, Kato K, Morio T, Yabe H; Inherited Disease Working Group of the Japan Society for Hematopoietic Cell Transplantation. Comparison of second transplantation and donor lymphocyte infusion for donor mixed chimerism after allogeneic stem cell transplantation for nonmalignant diseases. Pediatr Blood Cancer. 63:2221-2229, 2016
 
Inagaki J, Moritake H, Nishikawa T, Hyakuna N, Okada M, Suenobu SI, Nagai K, Honda Y, Shimomura M, Fukano R, Noguchi M, Kurauchi K, Tanioka S, Okamura J. Long-Term Morbidity and Mortality in Children with Chronic Graft-versus-Host Disease Classified by National Institutes of Health Consensus Criteria after Allogeneic Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. doi: 10.1016/j.bbmt.2015.07.025, 2015
 
Moritake H, Obara M, Sameshima N, Asada Y, Komatsu H, Hyakuna N, Sugita K, Ishida Y, Kato M, Tanizawa A, Deguchi T, Imamura T, Kitanaka A, Shimoda K, Kamimura S, Nunoi H. Analysis of the molecular mechanism underlying bone marrow necrosis with acute lymphoblastic leukemia. Int J Hematol. 102:349-56, 2015
 
Umeda K, Adachi S, Tanaka S, Ogawa A, Hatakeyama N, Kudo K, Sakata N, Igarashi S, Ohshima K, Hyakuna N, Chin M, Goto H, Takahashi Y, Azuma E, Koh K, Sawada A, Kato K, Inoue M, Atsuta Y, Takami A, Murata M; on behalf of the GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation. Comparison of continuous and twice-daily infusions of cyclosporine A for graft-versus-host-disease prophylaxis in pediatric hematopoietic stem cell transplantation. Pediatr Blood Cancer. doi: 10.1002/pbc.25243, 2014
 
Mizoguchi Y, Tsumura M, Okada S, Hirata O, Minegishi S, Imai K, Hyakuna N, Muramatsu H, Kojima S, Ozaki Y, Imai T, Takeda S, Okazaki T, Ito T, Yasunaga S, Takihara Y, Bryant VL, Kong XF, Cypowyj S, Boisson-Dupuis S, Puel A, Casanova JL, Morio T, Kobayashi M. Simple diagnosis of STAT1 gain-of-function alleles in patients with chronic mucocutaneous candidiasis. J Leukoc Biol. 95:667-76, 2014
 
Hyakuna N, Shimomura Y, Watanabe A, Taga T, Kikuta A, Matsushita T, Kogawa K, Kawakami C, Horikoshi Y, Iwai T, Okamoto Y, Tsurusawa M, Asami K; Japanese Childhood Cancer and Leukemia Study Group (JCCLSG). Assessment of corticosteroid-induced osteonecrosis in children undergoing chemotherapy for acute lymphoblastic leukemia: a report from the Japanese Childhood Cancer and Leukemia Study Group. J Pediatr Hematol Oncol. 36:22-9, 2014

Takahashi Y, Muramatsu H, Sakata N, Hyakuna N, Hamamoto K,  Kobayashi R, Ito E, Yagasaki H, Ohara A, Kikuchi A, Morimoto A, Yabe H, Kudo K, Watanabe K, Ohga S and Kojima S, on behalf of the Japan Childhood Aplastic Anemia Study Group. Rabbit antithymocyte globulin and cyclosporine as first-line therapy for children with acquired aplastic anemia. Blood  (in press, 2012)

Matsuda K, Yoshida N, Miura S, Nakazawa Y, Sakashita K, Hyakuna N, Saito M, Kato F, Ogawa A, Watanabe A, Sotomatsu M, Kobayashi C, Ito T, Ishida F, Manabe A, Kojima S, Koike K.  Long-term haematological improvement after non-intensive or no chemotherapy in juvenile myelomonocytic leukaemia and poor correlation with adult myelodysplasia spliceosome-related mutations. Br J Haematol. 2012;157:647-650, 2012
  
Shimomura Y, Baba R, Watanabe A, Horikoshi Y, Asami K, Hyakuna N, Iwai A, Matsushita T, Yamaji K, Hori T, Tsurusawa M; Japanese Childhood Cancer and Leukemia Study Group (JCCLSG).  Assessment of late cardiotoxicity of pirarubicin (THP) in children with acute lymphoblastic leukemia.  Pediatr Blood Cancer. 57:461-466, 2011
 
Yamaji K, Okamoto T, Yokota S, Watanabe A, Horikoshi Y, Asami K, Kikuta A, Hyakuna N, Saikawa Y, Ueyama J, Watanabe T, Okada M, Taga T, Kanegane H, Kogawa K, Chin M, Iwai A, Matsushita T, Shimomura Y, Hori T, Tsurusawa M.  Minimal residual disease-based augmented therapy in childhood acute lymphoblastic leukemia: a report from the Japanese Childhood Cancer and Leukemia Study Group. Pediatr Blood Cancer 55:1287-1295, 2010
 
百名伸之,比嘉 猛, 佐藤 将彰, 池原 由美子, 國島 伸治.MYH9異常を認めた巨大血小板性血小板減少症の1家系.日本小児血液学会雑誌24: 292-296,2010

Hamada, S., Umemuram M., Shiono, T., Hara, H., Kishihara, K., Tanaka, K., Mayuzumi, H., Ohta, T., Goro Matsuzaki. Importance of murine V?1+ ?? T cells expressing interferon-? and interleukin-17A in innate protection against Listeria monocytogenes infection. Immunology 125: 170-177, 2008

Hamada S, Umemura M, Shiono T, Tanaka K, Yahagi A, Begum MD, Oshiro K, Okamoto Y, Watanabe H, Kawakami K, Roark C, Born WK, O’Brien R, Ikuta K, Ishikawa H, Nkae S, Iwakura Y, Ohta T, Matsuzaki G. IL-17A produced by γδ T cells plays a critical role in innate immunity against Listeria monocytogenes infection in the liver. J Immunol 181: 3456-3463, 2008

Hyakuna N, Toguchi S, Higa T, Okudaira T, Taira N, Masuda M, Kitoh T, Ohta T. Childhood Blastic NK Cell Leukemia Successfully Treated with L-asparagenase and Allogenic Bone Marrow Transplantation. Pediatric Blood Cancer 42: 631-634, 2004